Collagen injections for musculoskeletal pain

At MEDANTE, we administer collagen injections (COLLAGEN MEDICAL DEVICES - 'MD' class) manufactured by the Italian company Guna, which has been involved in pharmaceutical research for over 20 years.

Guna traditionally uses substances natural to body in physiological concentrations and in combination with plant extracts and other natural substances. The concept is to naturally regulate, where necessary, the physiological functions of body.
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Guna MD - a complete range of products to treat the pain in the musculoskeletal and supporting apparatus.

They reduce pain and improve joint mobility by slowing the physiological degeneration of joints and associated tissues, always in the area for which they are intended. At the same time, they alleviate the damage caused by ageing, improper posture, accompanying chronic illnesses and injuries.

They contain collagen, which counteracts the flabbiness of connective tissue and substances of plant and mineral origin, which help transport the collagen to the target tissue.

Guna MD - kompletný rad prípravkov na liečbu bolesti pohybového a podporného aparátu.


  • Efficiency
  • Safety
  • Tolerance
  • No allergic reactions
  • Natural origin
  • For all ages
  • No risk of medication interactions
  • Possible to combine with other treatments

Complex effect on musculoskeletal pain.

The formulations are available in the packs of 10 ampoules. Not subject to medical prescription. Application is fast, minimally painful (subcutaneous, intradermic, intramuscular, intra-articular).

The standard protocol is to use one to two vials 2-3 times a week for the first two weeks, depending on severity and clinical condition; followed by one treatment per week until pain relief. Pain relief usually occurs after the first to third treatment.

GUNA MD collagen injections

In Slovakia, patients and doctors of various specializations (orthopaedists, neurologists, pain management doctors, surgeons, rheumatologists and general practitioners for adults) have experienced MD injections.

The main advantage of GUNA MD preparations is a gentle type of therapy for painful muscular tendons as well as for lumboischialgia syndrome. The collagen contained in the preparations is an excellent medication which, by means of regenerative and stimulating treatment, suppresses local inflammatory changes in tendons and joints, causing an analgesic reaction in the joint.

GUNA MD injections are easy to administer in small doses and well tolerated by patients. This treatment is recommended as an alternative to viscosupplementation with hyaluronic acid, corticosteroids, or oral therapy with analgesics, non-steroidal anti-rheumatic drugs and the like, with no major side effects reported.

The reported analgesic effect is 60-70%, potentiated by repeated application, after the application of the 9th - 10th injection, the analgesic effect is 89-90%.
Medante specialists
MUDr. Martina Frištáková, PhD.Orthopaedist
Dr. Zuzana Varínska ReinerRehabilitation doctor
Price list: Collagen injections for musculoskeletal pain
1 course of treatment (10 ampoules) of collagen including the application by the doctor
10ks á 15 min.245 €
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